What time does San Francisco 49ers-Arizona Cardinals NFL game start?
Kickoff is scheduled for Sunday, November 16, 2025 at 4:05 PM EST at State Farm Stadium.
Final score: Arizona Cardinals 22 — San Francisco 49ers 41.
What channel is San Francisco 49ers vs. Arizona Cardinals on tonight?
The Arizona Cardinals vs San Francisco 49ers game is broadcast across 12 broadcasters worldwide. Below you'll find a comprehensive broadcast partner list. Choose your preferred commentary language from the options below.
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2025 San Francisco 49ers schedule
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2025 Arizona Cardinals schedule
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2025 NFL team schedules: complete team-by-team schedule of games
Want the league-wide slate in one place? The NFL schedule hub lists every team's matchup in chronological order with national TV windows and streaming notes.